Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds 関連製品 (11050)
関連製品 (11050)
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α-Vitamin E-d11
0 Images製品番号: HY-N0683S6CAS 番号: 2874378-75-1別名: (+)-α-Tocopherol-d11; D-α-Tocopherol-d11α-Vitamin E-d11 ((+)-α-Tocopherol-d11) is the deuterium labeled α-Vitamin E (HY-N0683). α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant.
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1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phosphate-d7 sodium
0 Images製品番号: HY-146829SCAS 番号: 2260669-46-1別名: 15:0-18:1-PA-d71-Pentadecanoyl-2-oleoyl-sn-glycero-3-phosphate-d7 (sodium) is deuterium labeled 1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phosphate (sodium).
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DL-Arginine-15N4,d7 hydrochloride
0 Images製品番号: HY-W014375S別名: (±)-Arginine-15N4,d7 hydrochlorideDL-Arginine-15N4,d7 hydrochloride is deuterium and 15N labeled DL-Arginine hydrochloride (HY-W014375). DL-Arginine ((±)-Arginine) hydrochloride is the racemic compound of L-Arginine (HY-N0455) and D-Arginine (HY-W016781). Arginine is an essential amino acid that requires additional supplementation in traumatic or diseased conditions. Arginine is involved in T cell activation, proliferation, and differentiation, and affects the function of immune cells.
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6-Desacetyl-6-bromo-N-Boc Palbociclib-d4
0 Images製品番号: HY-132558SCAS 番号: 2089333-16-26-Desacetyl-6-bromo-N-Boc Palbociclib-d4 is the deuterium labeled 6-Desacetyl-6-bromo-N-Boc Palbociclib.
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Piperaquine-d6 tetraphosphate
0 Images製品番号: HY-118865SPiperaquine-d6 (tetraphosphate) is the deuterium labeled Piperaquine tetraphosphate. Piperaquine tetraphosphate is a bisquinoline antimalarial agent. Piperaquine phosphate can be used in antimalarial research in combination with Artemisinin.
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Pantoprazole-d8
0 Images製品番号: HY-17507S2CAS 番号: 934294-34-5別名: BY1023-d8; SKF96022-d8Pantoprazole-d8 (BY1023-d8) is deuterium labeled Pantoprazole. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI). Pantoprazole, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142).
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2-Acetylfuran-d3
0 Images製品番号: HY-W015912S別名: 2-Furyl methyl ketone-d32-Acetylfuran-d3 is deuterated labeled Citreoviridin (HY-N6745). Citreoviridin, a toxin from Penicillium citreoviride NRRL 2579, inhibits brain synaptosomal Na+/K+-ATPase whereas in microsomes, both Na+/K+-ATPase and Mg2+-ATPase activities are significantly stimulated in a dose-dependent manner. Citreoviridin inhibits cell proliferation and enhances apoptosis of human umbilical vein endothelial cells.
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5-Phenyl-5-(phenyl-d5)imidazolidine-2,4-dione
0 Images製品番号: HY-W721402CAS 番号: 63435-68-75-Phenyl-5-(phenyl-d5)imidazolidine-2,4-dione is deuterium-labeled 5-Phenyl-5-(phenyl-d5)imidazolidine-2,4-dione.
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Fmoc-Ile-OH-13C6,15N
0 Images別名: Fmoc-L-isoleucine-13C6,15NFmoc-Ile-OH-13C6,15N is the 13C and 15N labeled Fmoc-Ile-OH. Fmoc-Ile-OH is an isoleucine derivative.
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Acetazolamide-15N,d3
0 Images製品番号: HY-B0782S2CAS 番号: 1261393-93-4Acetazolamide-15N,d3 is the 15N and deuterium labeled isotope of Acetazolamide(15N,d3).
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N-[4-(2-Pyridinyl)benzoyl]glycine-13C2,15N
![N-[4-(2-Pyridinyl)benzoyl]glycine-13C2,15N](https://file.medchemexpress.com/product_pic/hy-144348s.gif "Click to View N-[4-(2-Pyridinyl)benzoyl]glycine-13C2,15N Product Detail")
0 Images製品番号: HY-144348SCAS 番号: 1391053-26-1N-[4-(2-Pyridinyl)benzoyl]glycine-13C2,15N is a 15N-labeled and 13C-labled labeled N-[4-(2-Pyridinyl)benzoyl]glycine.
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N-Desmethyl Olopatadine-d6
0 Images製品番号: HY-W741222SCAS 番号: 2012601-51-1N-Desmethyl Olopatadine-d6 is deuterium-labeled N-Desmethyl Olopatadine (HY-W741222).
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(Rac)-Vitamin B5,Calcium Salt Hydrate-13C3, 15N
0 Images製品番号: HY-150532S(Rac)-Vitamin B5,Calcium Salt Hydrate-13C3, 15N is the 13C and 15N labeled (Rac)-Vitamin B5,Calcium Salt Hydrate.
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Pazopanib-d3
0 Images製品番号: HY-10208S2CAS 番号: 1219591-97-5別名: GW786034-d3
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N-Benzylaniline-d2
0 Images製品番号: HY-W016321SCAS 番号: 136295-03-9別名: N-Phenylbenzylamine-d2; Benzylaniline-d2N-Benzylaniline-d2 (N-Phenylbenzylamine-d2) is the deuterium labeled N-Benzylaniline (HY-W016321). N-Benzylaniline is an N-alkyl-ated derivative of aniline.
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1-(Methylthio)-pentane-d3
0 Images製品番号: HY-W143071SCAS 番号: 3067019-21-71-(Methylthio)-pentane-d3 is the deuterium labeled Amyl methyl sulfide (HY-W143071).
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Fluorofenidone-d3
0 Images製品番号: HY-121246S別名: AKF-PD-d3Fluorofenidone-d3 (AKF-PD-d3) is deuterium labeled Fluorofenidone (AKF-PD) (HY-121246). Fluorofenidone is an orally active compound with anti-fibrotic, antioxidant, and anti-inflammatory pharmacological effects. Fluorofenidone downregulates the expression of ACSL4, upregulates GPX4 expression and inhibits the NF-κB signaling pathway to alleviate inflammation and fibrosis. Fluorofenidone ameliorates cholestasis and fibrosis by inhibiting hepatic Erk/-Egr-1 signaling and Tgfβ1/Smad pathway in mice. Fluorofenidone demonstrates protective effects against chronic lung injury in mice. Fluorofenidone can be used for the study of chronic obstructive pulmonary disease (COPD), pulmonary interstitial fibrosis (PIF) and non-small cell lung cancer (NSCLC).
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Naloxegol-13C,d2
0 Images製品番号: HY-A0118S1別名: NKTR-118-13C,d2; AZ-13337019-13C,d2Naloxegol-13C,d2 (NKTR-118-13C,d2) is 13C labeled Naloxegol. Naloxegol (NKTR-118; AZ-13337019) is a μ-opioid-receptor antagonist. Naloxegol inhibits opioid binding in μ-opioid receptors in the gastrointestinal tract and effective for alleviating opioid-induced constipation.
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Alvelestat-13C,d3
0 Images製品番号: HY-15651S別名: AZD9668-13C,d3Alvelestat-13C,d3 (AZD9668-13C,d3) is the deuterated, 13C-labeled Alvelestat (HY-15651). Alvelestat (AZD9668) is an orally active, selective inhibitor of neutrophil elastase. Alvelestat reduces elastase activity, myeloperoxidase release, neutrophil recruitment and activation, and calcium phosphate precipitation; promotes smooth muscle cell colonization and collagen deposition; and inhibits the formation of neutrophil extracellular traps (NETs) as well as NET-derived neutrophil elastase activity. Alvelestat restores endothelial dysfunction, regulates antioxidant factors, improves the expression of endothelial tight junctions, reduces vascular leakage, and accelerates wound healing. Alvelestat prevents pulmonary hemorrhage, matrix protein degradation, airspace enlargement, and small airway wall remodeling; and alleviates cigarette-induced inflammatory responses. Alvelestat inhibits the growth of abdominal aortic aneurysms exacerbated by Porphyromonas gingivalis. Alvelestat can be used in research related to chronic obstructive pulmonary disease, abdominal aortic aneurysm, radiation-induced skin injury, and bronchiectasis.
